Renue By Science Releases White Paper on Liposomal NAD+ and Methylene Blue Body Cream for Aging and Crepey Skin

JACKSONVILLE, Fla., Oct. 20, 2026 /PRNewswire/ -- Renue By Science, a longevity-focused wellness company specializing in NAD+ formulations, today announced the release of its latest whitepaper on Renue Blue Moisturizing Body Cream. The whitepaper reports results from a four-week consumer perception study, conducted with Citruslabs, of how women perceived changes in visible signs of body skin aging, including dryness, rough texture, fine lines, and crepey skin.

Dry, crepey, and less-firm skin on the arms, legs, and hands is one of the most common skin concerns among women over 30. Yet anti-aging research has focused mostly on the face, and products made for aging body skin have received far less study.

Renue Blue Moisturizing Body Cream was formulated to fill that gap. It combines longevity-focused ingredients, antioxidants, peptides, and botanical extracts. At its core is a liposomal complex of NAD+, NMN, NR, and Methylene Blue. Liposomal encapsulation is designed to help deliver these ingredients deeper into the skin for better absorption. Methylene Blue also works alongside CoQ10 and green tea extract as part of the formula's antioxidant defense. The rest of the formula is built around three goals:

• Hydration and comfort: Squalane, caprylic/capric triglycerides, and coconut oil help lock in moisture through the day.
• Barrier support: Rice lipids and chia seed extract help reinforce the skin's natural barrier.
• Firmness: Palmitoyl Tripeptide-5, together with NMN and NR, supports visibly firmer, more resilient skin.

In the new study, 40 women aged 30 to 65 with at least one self-reported visible sign of body skin aging applied the cream once daily for four weeks; 38 completed the study. Participants reported benefits early, and the benefits grew over time:

• Fast-acting hydration: 84% agreed their skin felt more hydrated by Day 3.
• Smoother, more even skin: 95% reported smoother skin at Week 4, and 89% reported improvement in rough or uneven areas.
• Visible aging concerns: 89% reported an improved appearance of fine lines, and 84% agreed crepey-looking areas appeared reduced and their skin felt firmer.
• Higher self-rated scores: On a 0–10 scale, mean hydration scores rose from 4.74 to 8.22, and mean scores for the appearance of crepey skin rose from 5.03 to 7.76.
• High satisfaction: 95% were satisfied with their results, and 92% would recommend the cream to family and friends.

"Body skin has been largely overlooked in skin aging research, even though concerns like crepey skin on the arms and legs come up constantly with the women we hear from," said Rebecca Crews, Ph.D., Research Director at Renue By Science. She added, "We built Renue Blue around liposomal NAD+ precursors and Methylene Blue, and we wanted to hear directly from women using it. Most noticed their skin felt more hydrated within just a few days, and the results kept improving over the four weeks."

Renue By Science is committed to developing science-backed products and to transparency in how they are evaluated. The company continues to invest in human research across its portfolio.

This was a virtual, single-arm consumer perception study; results reflect participants' self-reported perceptions.

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SOURCE Renue By Science