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Cognition Therapeutics Receives U.S. Patent Covering A Polymorph Version Of Its Lead Drug Candidate Zervimesine

Benzinga·10/13/2026 10:08:45
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The patent has a natural expiration of 2045. Upon zervimesine’s approval by the U.S. Food and Drug Administration (FDA), the patent may be eligible for an extension of up to five additional years.

The patent, titled "Crystalline forms of 2-(tert-butoxy)-4-(3-methyl-3-(5-(methylsulfonyl)isoindolin-2-yl)butyl)phenol fumarate salt," has been assigned U.S. Patent No. 12,759,979.

The ‘979 patent offers the following protections:

Composition of Matter: a polymorphic crystalline form of zervimesine.
Production Process: a proprietary process for producing this form of zervimesine.
Therapeutic Methods: methods of treating the age-related degenerative disorders Alzheimer’s disease, dry age-related macular degeneration (dry AMD), and dementia with Lewy bodies (DLB)