Pharvaris publishes Frontiers in Immunology study shaping Phase 3 CREAATE endpoints for acquired angioedema drug deucrictibant

• Pharvaris reported publication of qualitative study results in Frontiers in Immunology on disease burden in acquired angioedema due to C1 inhibitor deficiency.
• Findings highlighted frequent misdiagnosis, emergency care, painful attacks, major disruption to daily functioning, with patients relying on off-label treatments.
• The work supported use of established patient-reported outcomes as meaningful trial endpoints, helping define what patients consider improvement.
• Results have already been presented via publication, shaping the design and endpoint selection for the ongoing Phase 3 CREAATE trial of deucrictibant.
• Pharvaris positioned the study as a step toward patient-centered evidence in a condition with no approved preventive or on-demand therapies.

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