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Cytokinetics (CYTK): Evaluating Valuation After FDA Approval of First oHCM Therapy MYQORZO

Simply Wall St·12/25/2025 17:21:29
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The catalyst here is clear: Cytokinetics (CYTK) just secured FDA approval for MYQORZO, its first commercial therapy for symptomatic obstructive hypertrophic cardiomyopathy, turning years of clinical work into a real revenue opportunity.

See our latest analysis for Cytokinetics.

Investors have been repositioning around that catalyst all year, with the 90 day share price return of 34.18 percent and a 1 year total shareholder return of 32.25 percent suggesting momentum is building rather than fading at the current 64.18 dollars level.

If MYQORZO puts cardiovascular innovation on your radar, it could be a smart moment to scan other promising healthcare stocks and see what else is gaining traction.

With shares already up sharply, trading about 33 percent below consensus targets and only a modest discount to intrinsic value, the question now is whether Cytokinetics is still mispriced or if the market has fully discounted future growth.

Most Popular Narrative Narrative: 19.3% Undervalued

With Cytokinetics last closing at 64.18 dollars against a narrative fair value of 79.56 dollars, the story leans toward meaningful upside if assumptions hold.

The analysts have a consensus price target of $71.947 for Cytokinetics based on their expectations of its future earnings growth, profit margins and other risk factors. However, there is a degree of disagreement amongst analysts, with the most bullish reporting a price target of $120.0, and the most bearish reporting a price target of just $41.0.

Read the complete narrative.

Want to see what kind of hyper growth revenue ramp, margin shift and punchy future earnings multiple are baked into that upside path? The fine print may surprise you.

Result: Fair Value of $79.56 (UNDERVALUED)

Have a read of the narrative in full and understand what's behind the forecasts.

However, setbacks in aficamten’s regulatory path, or slower than expected uptake against entrenched cardiology standards, could quickly challenge this upside driven thesis.

Find out about the key risks to this Cytokinetics narrative.

Build Your Own Cytokinetics Narrative

If you see the story differently or want to test the assumptions yourself, you can build a personalized view in minutes: Do it your way.

A great starting point for your Cytokinetics research is our analysis highlighting 2 key rewards and 3 important warning signs that could impact your investment decision.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.