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    GRAIL (GRAL) Is Up 12.3% After Samsung-Backed Asian Galleri Deal And Trial Data - Has The Bull Case Changed?

    Simply Wall St·01/06/2026 15:27:23
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    • GRAIL recently reported that its Galleri multi-cancer early detection test achieved a 61.6% positive predictive value in the Pathfinder 2 clinical study, while also announcing a US$110 million investment and exclusive Asian distribution agreement with Samsung for Galleri, including South Korea.
    • This combination of encouraging clinical performance and Samsung’s regional backing highlights how both medical validation and distribution reach are becoming central to GRAIL’s commercial trajectory.
    • We’ll now examine how the Samsung-backed Asian distribution deal could reshape GRAIL’s investment narrative and future growth assumptions.

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    GRAIL Investment Narrative Recap

    To own GRAIL, you need to believe multi cancer early detection can become a routine part of care and that Galleri can win meaningful clinical, regulatory and payer acceptance. The latest Pathfinder 2 data and Samsung’s US$110.0 million investment support the near term catalyst of an FDA PMA filing for Galleri, but do not remove the key risk of continued high cash burn and ongoing unprofitability.

    Among recent announcements, the PATHFINDER 2 readout at ESMO, with a 61.6% positive predictive value and plans to submit data for FDA review, looks most tied to this Samsung news. Together, clinical validation and expanded distribution help frame how quickly GRAIL might translate promising science into reimbursed, real world test volumes, which remains central to any growth thesis.

    Yet even with Samsung’s backing, investors should be aware that continued high cash burn and persistent net losses could...

    Read the full narrative on GRAIL (it's free!)

    GRAIL's narrative projects $232.5 million revenue and $37.3 million earnings by 2028. This requires 20.1% yearly revenue growth and about a $480 million earnings increase from -$443.0 million today.

    Uncover how GRAIL's forecasts yield a $105.00 fair value, a 10% upside to its current price.

    Exploring Other Perspectives

    GRAL 1-Year Stock Price Chart
    GRAL 1-Year Stock Price Chart

    Five Simply Wall St Community fair value estimates for GRAIL span roughly US$28 to US$121 per share, highlighting very different views on upside. You are seeing those opinions form while Galleri’s clinical and regulatory path, including the FDA submission based on PATHFINDER data, could materially influence how the business ultimately scales.

    Explore 5 other fair value estimates on GRAIL - why the stock might be worth less than half the current price!

    Build Your Own GRAIL Narrative

    Disagree with existing narratives? Create your own in under 3 minutes - extraordinary investment returns rarely come from following the herd.

    • A great starting point for your GRAIL research is our analysis highlighting 1 key reward and 5 important warning signs that could impact your investment decision.
    • Our free GRAIL research report provides a comprehensive fundamental analysis summarized in a single visual - the Snowflake - making it easy to evaluate GRAIL's overall financial health at a glance.

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    This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.