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    What McKesson (MCK)'s Resilient Earnings Outlook Amid Market Weakness Means For Shareholders

    Simply Wall St·12/19/2025 00:37:39
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    • Earlier this week, investors reacted to McKesson’s upcoming earnings report, with consensus expecting a 14.45% rise in EPS and a 10.88% increase in quarterly revenue versus a year ago, while analysts reiterated a hold stance and signaled a favorable profitability outlook through recent estimate revisions.
    • The interesting angle is that this improved earnings outlook supported investor interest even as the broader market weakened, suggesting McKesson’s profit trajectory is currently being viewed as relatively resilient.
    • Next, we’ll examine how optimism around McKesson’s upcoming earnings and revised profit expectations interacts with its existing long-term investment narrative.

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    McKesson Investment Narrative Recap

    To own McKesson, you need to believe in steady long term demand for pharmaceuticals and medical supplies, and in its ability to convert that volume into growing earnings despite pricing pressure and consolidation across healthcare. The latest earnings optimism, reflected in expectations for higher EPS and revenue, supports the near term profit story but does not meaningfully change the key short term catalyst, which is continued margin improvement, or the main risk around potential drug pricing and policy shifts.

    Within that context, McKesson’s ongoing share repurchase activity, including US$824.35 million of buybacks in the most recent reported quarter, is particularly relevant. It amplifies the impact of any earnings growth on a per share basis, which ties directly into the current focus on profit resilience, but it does not remove longer term uncertainties around regulation or the possibility that vertical integration could erode the role of large wholesalers over time.

    However, investors should also be aware of how accelerating vertical integration among payers and PBMs could eventually reshape McKesson’s role in the supply chain and ...

    Read the full narrative on McKesson (it's free!)

    McKesson's narrative projects $478.8 billion revenue and $5.3 billion earnings by 2028.

    Uncover how McKesson's forecasts yield a $939.33 fair value, a 16% upside to its current price.

    Exploring Other Perspectives

    MCK 1-Year Stock Price Chart
    MCK 1-Year Stock Price Chart

    Five members of the Simply Wall St Community currently estimate McKesson’s fair value between about US$665 and US$1,399 per share, highlighting very different views on upside. Set those opinions against the current focus on earnings resilience and potential regulatory pressure on drug pricing, and it becomes clear why you may want to compare several perspectives before forming your own view.

    Explore 5 other fair value estimates on McKesson - why the stock might be worth as much as 73% more than the current price!

    Build Your Own McKesson Narrative

    Disagree with existing narratives? Create your own in under 3 minutes - extraordinary investment returns rarely come from following the herd.

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    This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.