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Does Telix (ASX:TLX) And Varian’s PSMA-PET Tie-Up Redefine Its Radiotherapy Moat?

Simply Wall St·12/12/2025 04:40:09
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  • Telix Pharmaceuticals recently announced a clinical collaboration with Varian, a Siemens Healthineers company, to combine its theranostic radiopharmaceuticals with external beam radiation therapy, initially focusing on PSMA-PET imaging in prostate cancer.
  • This tie-up could broaden the role of nuclear medicine in radiation oncology by using Telix’s Gozellix and Illuccix to sharpen patient selection and treatment planning.
  • Next, we’ll examine how this Varian collaboration around PSMA-PET-guided prostate radiotherapy shapes Telix’s investment narrative and risk profile.

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What Is Telix Pharmaceuticals' Investment Narrative?

To own Telix, you have to believe in the long-term payoff from building a full theranostics ecosystem around PSMA imaging and targeted radiopharmaceuticals, despite lumpier near-term execution. The new Varian collaboration fits that story neatly, plugging Illuccix and Gozellix directly into external beam radiotherapy workflows and potentially reinforcing Telix’s role in prostate cancer care rather than changing the core investment case overnight. Near term, the more tangible catalysts still sit around execution on Illuccix and Gozellix reimbursement and uptake, progress on TLX591’s ProstACT Global Phase 3, and regulatory milestones such as the TLX101-CDx resubmission. Against that, Telix’s recent profitability is fragile, margins have compressed, and the overhang from SEC scrutiny and securities class actions keeps legal and governance risk firmly on the table.

However, one set of risks around legal actions and prior disclosures is easy to underestimate. Despite retreating, Telix Pharmaceuticals' shares might still be trading above their fair value and there could be some more downside. Discover how much.

Exploring Other Perspectives

ASX:TLX 1-Year Stock Price Chart
ASX:TLX 1-Year Stock Price Chart
The Simply Wall St Community’s 40 fair value estimates for Telix span A$16.31 to A$64, reflecting very different views on upside. Set that against the recent securities lawsuits and margin compression, and it becomes clear why many investors are weighing both clinical partnerships and credibility risks before forming a view.

Explore 40 other fair value estimates on Telix Pharmaceuticals - why the stock might be worth just A$16.31!

Build Your Own Telix Pharmaceuticals Narrative

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.